Everything about small fiber neuropathy



Neuropathy is a basic term signifying disruptions in the regular functioning of the peripheral nerves. The reasons for neuropathy are diverse therefore is the treatment. Numerous a times, the neuropathy is practically irreparable and the treatment is mainly concentrated on preventing more development of the nerve damage and other supportive measures to avoid any problems due to neuropathy.

Neuropathies due to nutritional deficiencies are mainly treated with the replenishment of the lacking nutrient. Neuropathies due to shortage of vitamins like cobalamin, thiamine, pyridoxine, niacin are dealt with by giving the vitamin supplementation orally or by intramuscular injection of the vitamin if deficiency is due to defective absorption of vitamins from the diet. Treatment might or may not completely reverse the neuropathy and minimize the symptoms and in most cases there is some irreversible damage to nerves and consistent signs despite treatment. Recently neuropathy due to copper deficiency has also been found. It too is treated with oral copper salts or intravenous injection of copper salts. Again the action is variable and might take lots of months.

Entrapment neuropathies like carpal tunnel syndrome, radial neuropathy, meralgia paraesthetica, etc are treated based on particular cause and the nerve included. Again, each neuropathy is special and treatment is variable.

The treatment of neuropathies secondary to other illness is the treatment of the primary disease triggering the neuropathy. If neuropathy is due to Myxedema, caused by absence of thyroid hormonal agent, then treatment is replacing the thyroid hormonal agent. Treatment of Diabetic Neuropathy is generally supportive.

Treatment of neuropathy due to food allergic reaction is preventing the allergen food item causing neuropathy. Neuropathy might also be because of harmful result of particular drugs like Chloroquine, Phenytoin, anti-Cancer drugs and various others. Treatment in this case is mainly discontinuation of the drug or dosage decrease. There may be some particular treatment in particular cases, like neuropathy due to isoniazid can typically be avoided by giving pyridoxine in addition to it.


Numerous a times, the neuropathy is practically irreversible and the treatment is generally focused on preventing additional development of the nerve damage and other supportive procedures to prevent any problems due to neuropathy.

Entrapment neuropathies like carpal tunnel syndrome, radial neuropathy, meralgia paraesthetica, etc are dealt with based on particular cause and the nerve involved. The treatment of neuropathies secondary to other illness is the treatment of the main disease triggering the neuropathy. Treatment of neuropathy due to food allergy is preventing the allergen food product causing neuropathy.

Whatever the initial cause, your nerves responded with the only survival tool they had: they contracted, they reduced their length and volume to protect themselves, and the spaces between the nerves(synapse) were extended. A regular sized nerve signal might no longer leap this gap. Therefore nerve impulses, both those going up to the brain and those coming down from the brain were impaired.

Integrated microprocessors measures several physiological functions of your nerves and immediately changes itself to your particular therapeutic requirements, starting with the first healing signal.

When the system is very first switched on, it determines the electrical analog resistance and digital impedance and sets its output criteria for your physical mass. It knows if it is treating a 125 pound lady or a 350 lb male. It understands that if you use it straight on your lower back.

Specialized stimulator then sends a "test" signal that represents the most common waveform for healthy peripheral nerves. This signal goes from one foot, up the leg, to the nerve roots in your lower back, down the other leg, to the other foot. It then waits on an echo-like reaction from this preliminary signal.
It then evaluates this 'return" signal to figure out any aberrations.

Simply as a cardiologist can take one take a look at the shape of the signal displayed on an EKG monitor, and identify what is wrong with the heart, we have actually had the ability to recognize that the peripheral nerves have a very particular shape to its waveform. We can detect the nature of the issue by evaluating that waveform. This feature is built into the stimulator and processed by its internal microprocessor.

Irregularities in the shape of the waveform on the way up shows issues with numbness; the shape of the top of the waveform shows the ability of the nerve to provide the signal long enough for the brain to get everything; irregularities in the down slope of the waveform suggests pain, and the shape of the refractory duration as the nerve cell repolarize's itself suggests the ability of the nerve path to prepare for the next signal.

The gadget should then create, and send, a compensating waveform, to 'smooth out' these abnormalities, very much like the way noise canceling headphones work.

This process goes on 7.83 times every 2nd, sending out a signal, analyzing the returning signal, producing a compensating signal, and sending this new signal. It is constantly examining your reaction, and adjusting itself, to carefully coax your nerve's capability to send out and get correct signals.

These impulses are sent 7.83 times per second since that is the length of time it takes for the nerve cell to re-polarize (or reset) itself between its transmission of nerve signals. Minerals like potassium, sodium, and calcium must pass back and forth through the cell wall of the nerves. Very similar to a 'common' TENS device, the specialized neuromuscular stimulator signals are greatly more accurate and regulated. Commons TENS gadgets utilize an abnormal, uncontrolled, simple signal at a much higher frequency, specifically created to stop the cells capability to repolarize. This is why a typical 10S simply blocks the nerve signals. This device is a really customized type of 10S, which restores the neuropathy client.

The signals, (as they cross the synaptic junctions in the nerve roots of the lower back to get from one leg to the other), produce a little electro-magnetic field that is picked up by the nerves in your main nervous system (spine) and a signal is submitted to the brain to let it know exactly what is happening in the lumbar area. The brain then releases endorphins, internal discomfort reducers that take a trip through the blood stream to all parts of the body. These endorphins briefly alleviate pain in other parts of the body and assistance elevate your state of mind. These endorphin regulated advantages are palliative, and last for about 4 hours, offerring extra welcome remedy for your peripheral neuropathy pain.


Whatever the original cause, your nerves responded with the only survival tool they had: they contracted, they lowered their length and volume to preserve themselves, and the spaces in between the nerves(synapse) were extended. A normal sized nerve signal might no longer leap this gap. Specialized stimulator then sends out a "test" signal that represents the most more info common waveform for healthy peripheral nerves. These impulses are sent 7.83 times per 2nd since that is how long it takes for the nerve cell to re-polarize (or reset) itself in between its transmission of nerve signals. The signals, (as they cross the synaptic junctions in the nerve roots of the lower back to get from one leg to the other), produce a small electromagnetic field that is sensed by the nerves in your main anxious system (spinal column) and a signal is submitted to the brain to let it understand what is occurring in the lumbar location.

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